Topics in Molecular and Cellular Biology (ΜCB), 10 ECTS, total teaching hours 46 + 4 for literature theme presentations by MSc students
Aims: Interconnection of basic principles of biology with current research developments and approaches in molecular and cellular biology.
Sections:
[1] Cellular organization and function.
[2] Genomes and gene regulation.
Themes taught and (approximate) duration:
a) Cellular organization and function
Evolution, Molecular evolution (3h), Chromatin, nuclear envelope and nucleo-cytoplasmic traffic (3h), Biosynthetic secretory pathway (2h), Mechanisms of vesicle-mediated exocytosis, Extracellular vesicles (2h), Endocytosis: mechanisms and role in regulation of cellular function (3h), Transmembrane transport (2h), Mitochondrial transporters in human physiology and pathology (2h), Ion channels and neurological disorders (2h), The role of cytoskeleton in cellular functions (2h), Mitotic spindle organization (2h).
b) Genomes and gene regulation
Genome organization and evolution (2h), Bioinformatic genome analysis (2h), Transposable elements and diseases (2h), Mechanisms of gene expression regulation, RNA-dependent regulation of transcription and translation (2h), The role of translational control in nervous system function (2h), Cell cycle regulation, Cell cycle in oocytes and in egg cells (3h), Cell signaling: The PI3K/PTEN pathway (2h), The Wnt pathway (2h), The role of NO in regulation of metabolism (2h).